S-adenosyl-L-methionine (SAMe) is a compound found naturally in the body. SAMe helps produce and regulate hormones and maintain cell membranes. SAMe tablets are use to treat osteoarthritis, liver disease and depression. However, SAMe can also interact with antidepressant medications.
Osteoarthritis. Taking SAMe by mouth seems to work about aswell as aspirin and similar medications for reducing symptoms ofosteoarthritis. But it can take twice as long to start working.